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A gene for autosomal dominant hypohidrotic ectodermal dysplasia (EDA3) maps to chromosome 2q11-q13.
Am J Hum Genet. 1998 May; 62(5):1102-6.AJ

Abstract

Autosomal dominant hypohidrotic ectodermal dysplasia (ADHED) is a disorder characterized by fine, slow-growing scalp and body hair, sparse eyebrows and eyelashes, decreased sweating, hypodontia, and nail anomalies. By genetic linkage analysis of a large ADHED kindred, we have mapped a gene for ADHED (EDA3) to the proximal long arm of chromosome 2 (q11-q13). Obligate recombinations localize EDA3 to an approximately 9-cM interval between D2S1321 and D2S308, with no apparent recombinations with markers D2S1343, D2S436, D2S293, D2S1894, D2S1784, D2S1890, D2S274, and CHLC.GAAT11C03.

Authors+Show Affiliations

Department of Medical Genetics, University of Wisconsin, Madison, WI 53706, USA.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

9545409

Citation

Ho, L, et al. "A Gene for Autosomal Dominant Hypohidrotic Ectodermal Dysplasia (EDA3) Maps to Chromosome 2q11-q13." American Journal of Human Genetics, vol. 62, no. 5, 1998, pp. 1102-6.
Ho L, Williams MS, Spritz RA. A gene for autosomal dominant hypohidrotic ectodermal dysplasia (EDA3) maps to chromosome 2q11-q13. Am J Hum Genet. 1998;62(5):1102-6.
Ho, L., Williams, M. S., & Spritz, R. A. (1998). A gene for autosomal dominant hypohidrotic ectodermal dysplasia (EDA3) maps to chromosome 2q11-q13. American Journal of Human Genetics, 62(5), 1102-6.
Ho L, Williams MS, Spritz RA. A Gene for Autosomal Dominant Hypohidrotic Ectodermal Dysplasia (EDA3) Maps to Chromosome 2q11-q13. Am J Hum Genet. 1998;62(5):1102-6. PubMed PMID: 9545409.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A gene for autosomal dominant hypohidrotic ectodermal dysplasia (EDA3) maps to chromosome 2q11-q13. AU - Ho,L, AU - Williams,M S, AU - Spritz,R A, PY - 1998/5/23/pubmed PY - 2000/3/21/medline PY - 1998/5/23/entrez SP - 1102 EP - 6 JF - American journal of human genetics JO - Am J Hum Genet VL - 62 IS - 5 N2 - Autosomal dominant hypohidrotic ectodermal dysplasia (ADHED) is a disorder characterized by fine, slow-growing scalp and body hair, sparse eyebrows and eyelashes, decreased sweating, hypodontia, and nail anomalies. By genetic linkage analysis of a large ADHED kindred, we have mapped a gene for ADHED (EDA3) to the proximal long arm of chromosome 2 (q11-q13). Obligate recombinations localize EDA3 to an approximately 9-cM interval between D2S1321 and D2S308, with no apparent recombinations with markers D2S1343, D2S436, D2S293, D2S1894, D2S1784, D2S1890, D2S274, and CHLC.GAAT11C03. SN - 0002-9297 UR - https://wwww.unboundmedicine.com/medline/citation/9545409/A_gene_for_autosomal_dominant_hypohidrotic_ectodermal_dysplasia__EDA3__maps_to_chromosome_2q11_q13_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0002-9297(07)61531-6 DB - PRIME DP - Unbound Medicine ER -