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[Poisoning with Jimson weed. Five cases treated with physostigmine].
Tidsskr Nor Laegeforen. 1997 Aug 10; 117(18):2610-2.TN

Abstract

During the autumn of 1995, the National Poisons Information Centre was contacted about several cases of poisoning with Jimson weed (Datura stramonium). Five cases are described here. Upon admission to hospital the patients had moderate to severe anticholinergic symptoms, such as mydriasis, sinus tachycardia, agitation, dry mouth, urine retention, fever, hypertension, hallucinations and seizures. Owing to their agitated behaviour, gastrointestinal decontamination was impossible. Repeated doses of physostigmine (2-3 mg) administered intravenously reversed the anticholinergic features without side-effects. In the most severe case, physostigmine was needed for 18 hours (total dose; 25.5 mg). The patients recovered in a day or two, but mydriasis persisted in many cases.

Authors+Show Affiliations

Medisinsk avdeling Hedmark sentralsykehus.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

nor

PubMed ID

9324814

Citation

Amlo, H, et al. "[Poisoning With Jimson Weed. Five Cases Treated With Physostigmine]." Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, vol. 117, no. 18, 1997, pp. 2610-2.
Amlo H, Haugeng KL, Wickstrøm E, et al. [Poisoning with Jimson weed. Five cases treated with physostigmine]. Tidsskr Nor Laegeforen. 1997;117(18):2610-2.
Amlo, H., Haugeng, K. L., Wickstrøm, E., Koss, A., Husebye, T., & Jacobsen, D. (1997). [Poisoning with Jimson weed. Five cases treated with physostigmine]. Tidsskrift for Den Norske Laegeforening : Tidsskrift for Praktisk Medicin, Ny Raekke, 117(18), 2610-2.
Amlo H, et al. [Poisoning With Jimson Weed. Five Cases Treated With Physostigmine]. Tidsskr Nor Laegeforen. 1997 Aug 10;117(18):2610-2. PubMed PMID: 9324814.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Poisoning with Jimson weed. Five cases treated with physostigmine]. AU - Amlo,H, AU - Haugeng,K L, AU - Wickstrøm,E, AU - Koss,A, AU - Husebye,T, AU - Jacobsen,D, PY - 1997/8/10/pubmed PY - 1997/11/5/medline PY - 1997/8/10/entrez SP - 2610 EP - 2 JF - Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke JO - Tidsskr Nor Laegeforen VL - 117 IS - 18 N2 - During the autumn of 1995, the National Poisons Information Centre was contacted about several cases of poisoning with Jimson weed (Datura stramonium). Five cases are described here. Upon admission to hospital the patients had moderate to severe anticholinergic symptoms, such as mydriasis, sinus tachycardia, agitation, dry mouth, urine retention, fever, hypertension, hallucinations and seizures. Owing to their agitated behaviour, gastrointestinal decontamination was impossible. Repeated doses of physostigmine (2-3 mg) administered intravenously reversed the anticholinergic features without side-effects. In the most severe case, physostigmine was needed for 18 hours (total dose; 25.5 mg). The patients recovered in a day or two, but mydriasis persisted in many cases. SN - 0029-2001 UR - https://wwww.unboundmedicine.com/medline/citation/9324814/[Poisoning_with_Jimson_weed__Five_cases_treated_with_physostigmine]_ L2 - https://medlineplus.gov/druguseandaddiction.html DB - PRIME DP - Unbound Medicine ER -