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Physostigmine salicylate as an antidote.
Int J Clin Pharmacol Ther Toxicol. 1980 Dec; 18(12):523-35.IJ

Abstract

Most poisonings with anticholinergics deal with simple cases without diagnostic or therapeutic difficulties; however, in difficult or unclarified cases a new method for diagnosis and treatment is the antidote physostigmine salicylate. Within 15 minutes after application of 2 mg of the antidote the central anticholinergic symptoms disappear, such as respiratory depression, coma, cramps and hallucinations as do the peripheral anticholinergic symptoms as cardiac rhythm disturbance, dry mouth and red dry skin. No fatal overdose with anticholinergic drugs occurs if the antidote is given in time.

Authors

No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

7228447

Citation

Daunderer, M. "Physostigmine Salicylate as an Antidote." International Journal of Clinical Pharmacology, Therapy, and Toxicology, vol. 18, no. 12, 1980, pp. 523-35.
Daunderer M. Physostigmine salicylate as an antidote. Int J Clin Pharmacol Ther Toxicol. 1980;18(12):523-35.
Daunderer, M. (1980). Physostigmine salicylate as an antidote. International Journal of Clinical Pharmacology, Therapy, and Toxicology, 18(12), 523-35.
Daunderer M. Physostigmine Salicylate as an Antidote. Int J Clin Pharmacol Ther Toxicol. 1980;18(12):523-35. PubMed PMID: 7228447.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Physostigmine salicylate as an antidote. A1 - Daunderer,M, PY - 1980/12/1/pubmed PY - 1980/12/1/medline PY - 1980/12/1/entrez SP - 523 EP - 35 JF - International journal of clinical pharmacology, therapy, and toxicology JO - Int J Clin Pharmacol Ther Toxicol VL - 18 IS - 12 N2 - Most poisonings with anticholinergics deal with simple cases without diagnostic or therapeutic difficulties; however, in difficult or unclarified cases a new method for diagnosis and treatment is the antidote physostigmine salicylate. Within 15 minutes after application of 2 mg of the antidote the central anticholinergic symptoms disappear, such as respiratory depression, coma, cramps and hallucinations as do the peripheral anticholinergic symptoms as cardiac rhythm disturbance, dry mouth and red dry skin. No fatal overdose with anticholinergic drugs occurs if the antidote is given in time. SN - 0174-4879 UR - https://wwww.unboundmedicine.com/medline/citation/7228447/Physostigmine_salicylate_as_an_antidote_ DB - PRIME DP - Unbound Medicine ER -