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Castor bean toxicity re-examined: a new perspective.
Vet Hum Toxicol. 1985 Dec; 27(6):498-502.VH

Abstract

Commonly used references present a very gloomy prognosis for castor seed ingestion. This appears to be based chiefly on extrapolations from laboratory animal studies of toxicity of the component, ricin. This is not in concordance with actual experience when actual case report experience is sought out and examined in detail. The literature has been confused by recursive references among secondary sources and mortality statistics have been distorted by reliance on data generated nearly a century ago which do not accurately reflect the capabilities of modern medical management. This is elucidated by actually tracking down and studying difficult-to-find original case reports from the early decades of the 20th century. It is time to reappraise our estimates of the hazard of ingesting castor seeds in the light of present day medical capabilities.

Authors

No affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

4082461

Citation

Rauber, A, and J Heard. "Castor Bean Toxicity Re-examined: a New Perspective." Veterinary and Human Toxicology, vol. 27, no. 6, 1985, pp. 498-502.
Rauber A, Heard J. Castor bean toxicity re-examined: a new perspective. Vet Hum Toxicol. 1985;27(6):498-502.
Rauber, A., & Heard, J. (1985). Castor bean toxicity re-examined: a new perspective. Veterinary and Human Toxicology, 27(6), 498-502.
Rauber A, Heard J. Castor Bean Toxicity Re-examined: a New Perspective. Vet Hum Toxicol. 1985;27(6):498-502. PubMed PMID: 4082461.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Castor bean toxicity re-examined: a new perspective. AU - Rauber,A, AU - Heard,J, PY - 1985/12/1/pubmed PY - 1985/12/1/medline PY - 1985/12/1/entrez SP - 498 EP - 502 JF - Veterinary and human toxicology JO - Vet Hum Toxicol VL - 27 IS - 6 N2 - Commonly used references present a very gloomy prognosis for castor seed ingestion. This appears to be based chiefly on extrapolations from laboratory animal studies of toxicity of the component, ricin. This is not in concordance with actual experience when actual case report experience is sought out and examined in detail. The literature has been confused by recursive references among secondary sources and mortality statistics have been distorted by reliance on data generated nearly a century ago which do not accurately reflect the capabilities of modern medical management. This is elucidated by actually tracking down and studying difficult-to-find original case reports from the early decades of the 20th century. It is time to reappraise our estimates of the hazard of ingesting castor seeds in the light of present day medical capabilities. SN - 0145-6296 UR - https://wwww.unboundmedicine.com/medline/citation/4082461/Castor_bean_toxicity_re_examined:_a_new_perspective_ DB - PRIME DP - Unbound Medicine ER -