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Implementation of a Nurse-Led Etelcalcetide Protocol at the Outpatient Dialysis Unit: A Quality Improvement Project.
Nephrol Nurs J. 2022 Sep-Oct; 49(5):437-450.NN

Abstract

This quality improvement project was implemented to improve renal hyperparathyroidism in patients with end stage kidney disease who are on hemodialysis through the implementation of a nurse-led etelcalcetide protocol. Results showed that the post-intervention group had a 16.7% increase of the intact parathyroid hormone (iPTH) range within the target goal compared to the 3-month pre-intervention assessment (95% CI; 20.3% to 48.1%). The odds of being in the PTH target range were 1.73 times higher after the 3-month intervention than measurements obtained before starting the intervention (95% CI for the odds ratio: 0.29 to 10.3). Despite the lack of statistical significance (p = 0.688) due to a small sample size, there was an improvement in reaching goal PTH levels. Further studies are needed to analyze the effectiveness of nurse-led protocols in treating renal hyperparathyroidism in dialysis patients.

Authors+Show Affiliations

Nephrology Nurse Practitioner, Mayo Clinic, Jacksonville, FL. member of ANNA's North Central Florida Chapter.

Pub Type(s)

Journal Article

Language

eng

PubMed ID

36332124

Citation

Dalessandro, Lidia. "Implementation of a Nurse-Led Etelcalcetide Protocol at the Outpatient Dialysis Unit: a Quality Improvement Project." Nephrology Nursing Journal : Journal of the American Nephrology Nurses' Association, vol. 49, no. 5, 2022, pp. 437-450.
Dalessandro L. Implementation of a Nurse-Led Etelcalcetide Protocol at the Outpatient Dialysis Unit: A Quality Improvement Project. Nephrol Nurs J. 2022;49(5):437-450.
Dalessandro, L. (2022). Implementation of a Nurse-Led Etelcalcetide Protocol at the Outpatient Dialysis Unit: A Quality Improvement Project. Nephrology Nursing Journal : Journal of the American Nephrology Nurses' Association, 49(5), 437-450.
Dalessandro L. Implementation of a Nurse-Led Etelcalcetide Protocol at the Outpatient Dialysis Unit: a Quality Improvement Project. Nephrol Nurs J. 2022 Sep-Oct;49(5):437-450. PubMed PMID: 36332124.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Implementation of a Nurse-Led Etelcalcetide Protocol at the Outpatient Dialysis Unit: A Quality Improvement Project. A1 - Dalessandro,Lidia, PY - 2022/11/4/entrez PY - 2022/11/5/pubmed PY - 2022/11/9/medline KW - etelcalcetide KW - nurse protocol KW - nurse-led protocol KW - quality improvement project KW - renal hyperparathyroidism KW - secondary hyperparathyroidism SP - 437 EP - 450 JF - Nephrology nursing journal : journal of the American Nephrology Nurses' Association JO - Nephrol Nurs J VL - 49 IS - 5 N2 - This quality improvement project was implemented to improve renal hyperparathyroidism in patients with end stage kidney disease who are on hemodialysis through the implementation of a nurse-led etelcalcetide protocol. Results showed that the post-intervention group had a 16.7% increase of the intact parathyroid hormone (iPTH) range within the target goal compared to the 3-month pre-intervention assessment (95% CI; 20.3% to 48.1%). The odds of being in the PTH target range were 1.73 times higher after the 3-month intervention than measurements obtained before starting the intervention (95% CI for the odds ratio: 0.29 to 10.3). Despite the lack of statistical significance (p = 0.688) due to a small sample size, there was an improvement in reaching goal PTH levels. Further studies are needed to analyze the effectiveness of nurse-led protocols in treating renal hyperparathyroidism in dialysis patients. SN - 1526-744X UR - https://wwww.unboundmedicine.com/medline/citation/36332124/Implementation_of_a_Nurse_Led_Etelcalcetide_Protocol_at_the_Outpatient_Dialysis_Unit:_A_Quality_Improvement_Project_ DB - PRIME DP - Unbound Medicine ER -