Audiologic impairment associated with bilirubin-induced neurologic damage.Semin Fetal Neonatal Med. 2015 Feb; 20(1):42-46.SF
Abstract
Hyperbilirubinemia occurs commonly in neonates and is usually mild and transient, with no long-lasting sequelae. However, bilirubin-induced neurologic damage may occur in some infants. The auditory pathway is the most sensitive part of the central nervous system to bilirubin-induced toxicity, and permanent sequelae may result from only moderately elevated total serum/plasma bilirubin levels. The damage to the auditory system occurs primarily within the brainstem and cranial nerve VIII, and manifests clinically as auditory neuropathy spectrum disorder.
Links
MeSH
Pub Type(s)
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Language
eng
PubMed ID
25575899
Citation
Olds, Cristen, and John S. Oghalai. "Audiologic Impairment Associated With Bilirubin-induced Neurologic Damage." Seminars in Fetal & Neonatal Medicine, vol. 20, no. 1, 2015, pp. 42-46.
Olds C, Oghalai JS. Audiologic impairment associated with bilirubin-induced neurologic damage. Semin Fetal Neonatal Med. 2015;20(1):42-46.
Olds, C., & Oghalai, J. S. (2015). Audiologic impairment associated with bilirubin-induced neurologic damage. Seminars in Fetal & Neonatal Medicine, 20(1), 42-46. https://doi.org/10.1016/j.siny.2014.12.006
Olds C, Oghalai JS. Audiologic Impairment Associated With Bilirubin-induced Neurologic Damage. Semin Fetal Neonatal Med. 2015;20(1):42-46. PubMed PMID: 25575899.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR
T1 - Audiologic impairment associated with bilirubin-induced neurologic damage.
AU - Olds,Cristen,
AU - Oghalai,John S,
Y1 - 2015/01/07/
PY - 2015/1/11/entrez
PY - 2015/1/13/pubmed
PY - 2016/1/1/medline
KW - Auditory brainstem response
KW - Auditory neuropathy
KW - Bilirubin
KW - Hyperbilirubinemia
KW - Kernicterus
SP - 42
EP - 46
JF - Seminars in fetal & neonatal medicine
JO - Semin Fetal Neonatal Med
VL - 20
IS - 1
N2 - Hyperbilirubinemia occurs commonly in neonates and is usually mild and transient, with no long-lasting sequelae. However, bilirubin-induced neurologic damage may occur in some infants. The auditory pathway is the most sensitive part of the central nervous system to bilirubin-induced toxicity, and permanent sequelae may result from only moderately elevated total serum/plasma bilirubin levels. The damage to the auditory system occurs primarily within the brainstem and cranial nerve VIII, and manifests clinically as auditory neuropathy spectrum disorder.
SN - 1878-0946
UR - https://wwww.unboundmedicine.com/medline/citation/25575899/Audiologic_impairment_associated_with_bilirubin_induced_neurologic_damage_
DB - PRIME
DP - Unbound Medicine
ER -