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Jaundice and kernicterus in the moderately preterm infant.
Clin Perinatol. 2013 Dec; 40(4):679-88.CP

Abstract

Moderate preterm infants remain at increased risk for adverse outcomes, including acute bilirubin encephalopathy (ABE). Evidence-based guidelines for management of hyperbilirubinemia in preterm infants less than 35 weeks' gestational age are not yet optimized. High concentrations of unconjugated bilirubin can cause permanent posticteric neurologic sequelae (kernicterus). Clinical manifestations of ABE in preterm infants are similar to, but often more subtle than, those of term infants. This review outlines clinical strategies to operationalize management of hyperbilirubinemia in moderately preterm infants to meet recently published consensus-based recommendations.

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Authors+Show Affiliations

Wallenstein MB
Division of Neonatal-Developmental Medicine, Department of Pediatrics, Lucile Packard Children's Hospital, Stanford University School of Medicine, 750 Welch Road #315, Stanford, CA 94304, USA.
Bhutani VK
No affiliation info available

MeSH

BilirubinConsensusHumansHyperbilirubinemia, NeonatalInfant, NewbornInfant, PrematureInfant, Premature, DiseasesJaundice, NeonatalKernicterusPractice Guidelines as TopicReference Values

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

24182955

Citation

Wallenstein, Matthew B., and Vinod K. Bhutani. "Jaundice and Kernicterus in the Moderately Preterm Infant." Clinics in Perinatology, vol. 40, no. 4, 2013, pp. 679-88.
Wallenstein MB, Bhutani VK. Jaundice and kernicterus in the moderately preterm infant. Clin Perinatol. 2013;40(4):679-88.
Wallenstein, M. B., & Bhutani, V. K. (2013). Jaundice and kernicterus in the moderately preterm infant. Clinics in Perinatology, 40(4), 679-88. https://doi.org/10.1016/j.clp.2013.07.007
Wallenstein MB, Bhutani VK. Jaundice and Kernicterus in the Moderately Preterm Infant. Clin Perinatol. 2013;40(4):679-88. PubMed PMID: 24182955.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Jaundice and kernicterus in the moderately preterm infant. AU - Wallenstein,Matthew B, AU - Bhutani,Vinod K, Y1 - 2013/09/20/ PY - 2013/11/5/entrez PY - 2013/11/5/pubmed PY - 2014/7/18/medline KW - Bilirubin encephalopathy KW - Bilirubin-induced neurologic dysfunction KW - Hyperbilirubinemia KW - Jaundice KW - Kernicterus KW - Moderately preterm KW - Newborn jaundice SP - 679 EP - 88 JF - Clinics in perinatology JO - Clin Perinatol VL - 40 IS - 4 N2 - Moderate preterm infants remain at increased risk for adverse outcomes, including acute bilirubin encephalopathy (ABE). Evidence-based guidelines for management of hyperbilirubinemia in preterm infants less than 35 weeks' gestational age are not yet optimized. High concentrations of unconjugated bilirubin can cause permanent posticteric neurologic sequelae (kernicterus). Clinical manifestations of ABE in preterm infants are similar to, but often more subtle than, those of term infants. This review outlines clinical strategies to operationalize management of hyperbilirubinemia in moderately preterm infants to meet recently published consensus-based recommendations. SN - 1557-9840 UR - https://wwww.unboundmedicine.com/medline/citation/24182955/Jaundice_and_kernicterus_in_the_moderately_preterm_infant_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0095-5108(13)00081-X DB - PRIME DP - Unbound Medicine ER -