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[Gastroprotective properties of mexidol and hypoxen].
Eksp Klin Farmakol 2010; 73(5):15-8EK

Abstract

Experimental damage in the stomach mucosa of test rats was modeled by acetylsalicylic acid (aspirin-induced ulcerogenesis). The number of ulcers and the total area of erosive injury in the mucous membrane were studied. Prophylactic treatment with mexidol and hypoxen in a daily dose of 50 mg/kg reduces the aspirin-induced damage of stomach mucosa. The gastroprotective properties of drugs are probably related to their antioxidant and antihypoxant effects.

Authors

Novikov VE
No affiliation info available
Kriukova NO
No affiliation info available
Novikov AS
No affiliation info available

MeSH

AnimalsAnti-Inflammatory Agents, Non-SteroidalAntioxidantsAspirinGastric MucosaPhenyl EthersPicolinesRatsStomach Ulcer

Pub Type(s)

Journal Article

Language

rus

PubMed ID

20597364

Citation

Novikov, V E., et al. "[Gastroprotective Properties of Mexidol and Hypoxen]." Eksperimental'naia I Klinicheskaia Farmakologiia, vol. 73, no. 5, 2010, pp. 15-8.
Novikov VE, Kriukova NO, Novikov AS. [Gastroprotective properties of mexidol and hypoxen]. Eksp Klin Farmakol. 2010;73(5):15-8.
Novikov, V. E., Kriukova, N. O., & Novikov, A. S. (2010). [Gastroprotective properties of mexidol and hypoxen]. Eksperimental'naia I Klinicheskaia Farmakologiia, 73(5), pp. 15-8.
Novikov VE, Kriukova NO, Novikov AS. [Gastroprotective Properties of Mexidol and Hypoxen]. Eksp Klin Farmakol. 2010;73(5):15-8. PubMed PMID: 20597364.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Gastroprotective properties of mexidol and hypoxen]. AU - Novikov,V E, AU - Kriukova,N O, AU - Novikov,A S, PY - 2010/7/6/entrez PY - 2010/7/6/pubmed PY - 2010/7/21/medline SP - 15 EP - 8 JF - Eksperimental'naia i klinicheskaia farmakologiia JO - Eksp Klin Farmakol VL - 73 IS - 5 N2 - Experimental damage in the stomach mucosa of test rats was modeled by acetylsalicylic acid (aspirin-induced ulcerogenesis). The number of ulcers and the total area of erosive injury in the mucous membrane were studied. Prophylactic treatment with mexidol and hypoxen in a daily dose of 50 mg/kg reduces the aspirin-induced damage of stomach mucosa. The gastroprotective properties of drugs are probably related to their antioxidant and antihypoxant effects. SN - 0869-2092 UR - https://wwww.unboundmedicine.com/medline/citation/20597364/[Gastroprotective_properties_of_mexidol_and_hypoxen] L2 - https://medlineplus.gov/antioxidants.html DB - PRIME DP - Unbound Medicine ER -