Tags

Type your tag names separated by a space and hit enter

Fetal death of dogs after the ingestion of a soil conditioner.
Exp Toxicol Pathol. 2011 Jan; 63(1-2):113-7.ET

Abstract

Castor beans (Ricinus communis) contain ricin, which is one of the most toxic substances of plant origin. Ricin toxicosis has been reported in different countries with usually ingestion of castor beans or plants in both animals and humans. However, ricin toxicosis by ingestion of some products containing castor oil cake has rarely been reported. This paper describes outbreaks of dog death by ricin toxicosis after accidental ingestion of the same soil conditioner. Fifteen dogs showed toxic symptoms such as severe vomiting, abdominal pain and hemorrhagic diarrhea, and then thirteen dogs died in a few days. The soil conditioner dogs ingested consisted of 10% castor oil cake containing ricin. On the basis of clinical signs, laboratory and pathologic findings, a diagnosis of ricin toxicosis was established in the present case. In comparison with previous cases by ingestion of castor beans, the dogs' morbidity was very high in the present case. The ingestion of castor oil cake may be more dangerous to life than the castor beans. It is because mortality by ingestion of castor beans depends on the degree of mastication of the beans, whereas ricin in oil cake is easily absorbed from the stomach and the intestines. As ricin is a heat-labile toxin, products containing ricin or oil cake should be properly treated with heat and have written caution sentences about toxicosis, and be kept out of reach of domestic animals and children.

Authors+Show Affiliations

Department of Veterinary Pathology, College of Veterinary Medicine, Kyungpook National University, Daegu 702-701, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19932603

Citation

Hong, Il-Hwa, et al. "Fetal Death of Dogs After the Ingestion of a Soil Conditioner." Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie, vol. 63, no. 1-2, 2011, pp. 113-7.
Hong IH, Kwon TE, Lee SK, et al. Fetal death of dogs after the ingestion of a soil conditioner. Exp Toxicol Pathol. 2011;63(1-2):113-7.
Hong, I. H., Kwon, T. E., Lee, S. K., Park, J. K., Ki, M. R., Park, S. I., & Jeong, K. S. (2011). Fetal death of dogs after the ingestion of a soil conditioner. Experimental and Toxicologic Pathology : Official Journal of the Gesellschaft Fur Toxikologische Pathologie, 63(1-2), 113-7. https://doi.org/10.1016/j.etp.2009.10.004
Hong IH, et al. Fetal Death of Dogs After the Ingestion of a Soil Conditioner. Exp Toxicol Pathol. 2011;63(1-2):113-7. PubMed PMID: 19932603.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fetal death of dogs after the ingestion of a soil conditioner. AU - Hong,Il-Hwa, AU - Kwon,Tae-Eog, AU - Lee,Seung-Keun, AU - Park,Jin-Kyu, AU - Ki,Mi-Ran, AU - Park,Se-Il, AU - Jeong,Kyu-Shik, Y1 - 2009/11/22/ PY - 2009/07/30/received PY - 2009/09/01/revised PY - 2009/10/22/accepted PY - 2009/11/26/entrez PY - 2009/11/26/pubmed PY - 2011/4/5/medline SP - 113 EP - 7 JF - Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie JO - Exp Toxicol Pathol VL - 63 IS - 1-2 N2 - Castor beans (Ricinus communis) contain ricin, which is one of the most toxic substances of plant origin. Ricin toxicosis has been reported in different countries with usually ingestion of castor beans or plants in both animals and humans. However, ricin toxicosis by ingestion of some products containing castor oil cake has rarely been reported. This paper describes outbreaks of dog death by ricin toxicosis after accidental ingestion of the same soil conditioner. Fifteen dogs showed toxic symptoms such as severe vomiting, abdominal pain and hemorrhagic diarrhea, and then thirteen dogs died in a few days. The soil conditioner dogs ingested consisted of 10% castor oil cake containing ricin. On the basis of clinical signs, laboratory and pathologic findings, a diagnosis of ricin toxicosis was established in the present case. In comparison with previous cases by ingestion of castor beans, the dogs' morbidity was very high in the present case. The ingestion of castor oil cake may be more dangerous to life than the castor beans. It is because mortality by ingestion of castor beans depends on the degree of mastication of the beans, whereas ricin in oil cake is easily absorbed from the stomach and the intestines. As ricin is a heat-labile toxin, products containing ricin or oil cake should be properly treated with heat and have written caution sentences about toxicosis, and be kept out of reach of domestic animals and children. SN - 1618-1433 UR - https://wwww.unboundmedicine.com/medline/citation/19932603/Fetal_death_of_dogs_after_the_ingestion_of_a_soil_conditioner_ DB - PRIME DP - Unbound Medicine ER -