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Effect of short-term creatine supplementation on neuromuscular function.
Med Sci Sports Exerc. 2009 Oct; 41(10):1934-41.MS

Abstract

PURPOSE

The purpose of the present investigation was to determine whether short-term creatine (Cr) supplementation would affect 1) muscle contractile properties assessed by evoked and voluntary contractions, 2) force-velocity relationship, and 3) mean muscle fiber conduction velocity (CV).

METHODS

Using a double-blind random design, 16 moderately trained men (25.2 ± 5.1 yr) were assigned to a Cr (CRE) or a placebo (PLA) group. Subjects supplemented their diet four times a day for 5 d with 5 g of Cr + 15 g maltodextrin (CRE) or 20 g maltodextrin (PLA). Isometric maximal voluntary contraction, maximal twitch, force-velocity relationship, and dynamic fatiguing contractions were assessed in the elbow flexors. Mechanical and EMG signals were recorded and analyzed. CV was estimated from the EMG and used as a parameter of interest.

RESULTS

After supplementation, peak torque (PT) of maximal twitch was 33.4% higher, and the time to reach the PT was 54.7% lower in CRE than in PLA (P < 0.05). Torque-angular velocity curve was enhanced after Cr supplementation, especially at the higher velocities. Mean fiber CV was, on average, 8.9% higher in CRE at all angular velocities after supplementation (P < 0.05). EMG and mechanical parameters during the fatiguing exercise protocol did not show significant differences in muscle fatigue between the two groups after supplementation.

CONCLUSIONS

The present study shows that oral Cr supplementation improves neuromuscular function of the elbow flexor muscle during both voluntary and electrically induced contractions.

Authors+Show Affiliations

Department of Human Movement and Sport Sciences, Università degli Studi di Roma Foro Italico, Roma, Italy. ilenia.bazzucchi@iusm.itNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

19727018

Citation

Bazzucchi, Ilenia, et al. "Effect of Short-term Creatine Supplementation On Neuromuscular Function." Medicine and Science in Sports and Exercise, vol. 41, no. 10, 2009, pp. 1934-41.
Bazzucchi I, Felici F, Sacchetti M. Effect of short-term creatine supplementation on neuromuscular function. Med Sci Sports Exerc. 2009;41(10):1934-41.
Bazzucchi, I., Felici, F., & Sacchetti, M. (2009). Effect of short-term creatine supplementation on neuromuscular function. Medicine and Science in Sports and Exercise, 41(10), 1934-41. https://doi.org/10.1249/MSS.0b013e3181a2c05c
Bazzucchi I, Felici F, Sacchetti M. Effect of Short-term Creatine Supplementation On Neuromuscular Function. Med Sci Sports Exerc. 2009;41(10):1934-41. PubMed PMID: 19727018.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of short-term creatine supplementation on neuromuscular function. AU - Bazzucchi,Ilenia, AU - Felici,Francesco, AU - Sacchetti,Massimo, PY - 2009/9/4/entrez PY - 2009/9/4/pubmed PY - 2011/11/9/medline SP - 1934 EP - 41 JF - Medicine and science in sports and exercise JO - Med Sci Sports Exerc VL - 41 IS - 10 N2 - PURPOSE: The purpose of the present investigation was to determine whether short-term creatine (Cr) supplementation would affect 1) muscle contractile properties assessed by evoked and voluntary contractions, 2) force-velocity relationship, and 3) mean muscle fiber conduction velocity (CV). METHODS: Using a double-blind random design, 16 moderately trained men (25.2 ± 5.1 yr) were assigned to a Cr (CRE) or a placebo (PLA) group. Subjects supplemented their diet four times a day for 5 d with 5 g of Cr + 15 g maltodextrin (CRE) or 20 g maltodextrin (PLA). Isometric maximal voluntary contraction, maximal twitch, force-velocity relationship, and dynamic fatiguing contractions were assessed in the elbow flexors. Mechanical and EMG signals were recorded and analyzed. CV was estimated from the EMG and used as a parameter of interest. RESULTS: After supplementation, peak torque (PT) of maximal twitch was 33.4% higher, and the time to reach the PT was 54.7% lower in CRE than in PLA (P < 0.05). Torque-angular velocity curve was enhanced after Cr supplementation, especially at the higher velocities. Mean fiber CV was, on average, 8.9% higher in CRE at all angular velocities after supplementation (P < 0.05). EMG and mechanical parameters during the fatiguing exercise protocol did not show significant differences in muscle fatigue between the two groups after supplementation. CONCLUSIONS: The present study shows that oral Cr supplementation improves neuromuscular function of the elbow flexor muscle during both voluntary and electrically induced contractions. SN - 1530-0315 UR - https://wwww.unboundmedicine.com/medline/citation/19727018/Effect_of_short_term_creatine_supplementation_on_neuromuscular_function_ L2 - https://doi.org/10.1249/MSS.0b013e3181a2c05c DB - PRIME DP - Unbound Medicine ER -