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Witkop's tooth and nail syndrome: a multifaceted approach to dental management.
J Indian Soc Pedod Prev Dent. 2008 Mar; 26(1):22-5.JI

Abstract

Witkop's tooth and nail syndrome is a rare autosomal dominant disorder of ectodermal dysplasia characterized by hypodontia and nail dysplasia. Mutations in MSX-1 have been shown to be associated with this syndrome. There is failure of development and eruption of the dentition. Tooth shape may vary; the most common forms are conical and narrow crowns. The nails may be spoon shaped and slow growing and affect both finger and toe nails. The nail involvement is more severe in childhood. The present case describes a 14-year-old boy who showed the characteristic features of Witkop's syndrome. A multifaceted approach to the dental management of the patient is discussed.

Authors+Show Affiliations

Department of Pedodontics and Preventive Dentistry, The Oxford Dental College, Hospital and Research Center, Hosur Road, Bangalore, Karnataka, India. drpiyapedo@yahoo.comNo affiliation info available

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

18408267

Citation

Subramaniam, P, and G Neeraja. "Witkop's Tooth and Nail Syndrome: a Multifaceted Approach to Dental Management." Journal of the Indian Society of Pedodontics and Preventive Dentistry, vol. 26, no. 1, 2008, pp. 22-5.
Subramaniam P, Neeraja G. Witkop's tooth and nail syndrome: a multifaceted approach to dental management. J Indian Soc Pedod Prev Dent. 2008;26(1):22-5.
Subramaniam, P., & Neeraja, G. (2008). Witkop's tooth and nail syndrome: a multifaceted approach to dental management. Journal of the Indian Society of Pedodontics and Preventive Dentistry, 26(1), 22-5.
Subramaniam P, Neeraja G. Witkop's Tooth and Nail Syndrome: a Multifaceted Approach to Dental Management. J Indian Soc Pedod Prev Dent. 2008;26(1):22-5. PubMed PMID: 18408267.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Witkop's tooth and nail syndrome: a multifaceted approach to dental management. AU - Subramaniam,P, AU - Neeraja,G, PY - 2008/4/15/pubmed PY - 2008/12/17/medline PY - 2008/4/15/entrez SP - 22 EP - 5 JF - Journal of the Indian Society of Pedodontics and Preventive Dentistry JO - J Indian Soc Pedod Prev Dent VL - 26 IS - 1 N2 - Witkop's tooth and nail syndrome is a rare autosomal dominant disorder of ectodermal dysplasia characterized by hypodontia and nail dysplasia. Mutations in MSX-1 have been shown to be associated with this syndrome. There is failure of development and eruption of the dentition. Tooth shape may vary; the most common forms are conical and narrow crowns. The nails may be spoon shaped and slow growing and affect both finger and toe nails. The nail involvement is more severe in childhood. The present case describes a 14-year-old boy who showed the characteristic features of Witkop's syndrome. A multifaceted approach to the dental management of the patient is discussed. SN - 0970-4388 UR - https://wwww.unboundmedicine.com/medline/citation/18408267/Witkop's_tooth_and_nail_syndrome:_a_multifaceted_approach_to_dental_management_ DB - PRIME DP - Unbound Medicine ER -