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Antidote use in the critically ill poisoned patient.
J Intensive Care Med. 2006 Sep-Oct; 21(5):255-77.JI

Abstract

The proper use of antidotes in the intensive care setting when combined with appropriate general supportive care may reduce the morbidity and mortality associated with severe poisonings. The more commonly used antidotes that may be encountered in the intensive care unit (N-acetylcysteine, ethanol, fomepizole, physostigmine, naloxone, flumazenil, sodium bicarbonate, octreotide, pyridoxine, cyanide antidote kit, pralidoxime, atropine, digoxin immune Fab, glucagon, calcium gluconate and chloride, deferoxamine, phytonadione, botulism antitoxin, methylene blue, and Crotaline snake antivenom) are reviewed. Proper indications for their use and knowledge of the possible adverse effects accompanying antidotal therapy will allow the physician to appropriately manage the severely poisoned patient.

Authors+Show Affiliations

Department of Emergency Medicine, Sparrow Health System, Michigan State University College of Human Medicine, Lansing, Michigan 48912-1811, USA. peckb73@hotmail.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

16946442

Citation

Betten, David P., et al. "Antidote Use in the Critically Ill Poisoned Patient." Journal of Intensive Care Medicine, vol. 21, no. 5, 2006, pp. 255-77.
Betten DP, Vohra RB, Cook MD, et al. Antidote use in the critically ill poisoned patient. J Intensive Care Med. 2006;21(5):255-77.
Betten, D. P., Vohra, R. B., Cook, M. D., Matteucci, M. J., & Clark, R. F. (2006). Antidote use in the critically ill poisoned patient. Journal of Intensive Care Medicine, 21(5), 255-77.
Betten DP, et al. Antidote Use in the Critically Ill Poisoned Patient. J Intensive Care Med. 2006 Sep-Oct;21(5):255-77. PubMed PMID: 16946442.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antidote use in the critically ill poisoned patient. AU - Betten,David P, AU - Vohra,Rais B, AU - Cook,Matthew D, AU - Matteucci,Michael J, AU - Clark,Richard F, PY - 2006/9/2/pubmed PY - 2007/1/6/medline PY - 2006/9/2/entrez SP - 255 EP - 77 JF - Journal of intensive care medicine JO - J Intensive Care Med VL - 21 IS - 5 N2 - The proper use of antidotes in the intensive care setting when combined with appropriate general supportive care may reduce the morbidity and mortality associated with severe poisonings. The more commonly used antidotes that may be encountered in the intensive care unit (N-acetylcysteine, ethanol, fomepizole, physostigmine, naloxone, flumazenil, sodium bicarbonate, octreotide, pyridoxine, cyanide antidote kit, pralidoxime, atropine, digoxin immune Fab, glucagon, calcium gluconate and chloride, deferoxamine, phytonadione, botulism antitoxin, methylene blue, and Crotaline snake antivenom) are reviewed. Proper indications for their use and knowledge of the possible adverse effects accompanying antidotal therapy will allow the physician to appropriately manage the severely poisoned patient. SN - 0885-0666 UR - https://wwww.unboundmedicine.com/medline/citation/16946442/Antidote_use_in_the_critically_ill_poisoned_patient_ L2 - https://journals.sagepub.com/doi/10.1177/0885066606290386?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -