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Extracorporeal shockwave therapy for Peyronie's disease: an alternative treatment?
Asian J Androl. 2006 May; 8(3):361-6.AJ

Abstract

AIM

To determine retrospectively the safety and efficacy of extracorporeal shock wave therapy (ESWT) in patients with Peyronie's disease.

METHODS

Fifty-three patients with stable Peyronie's disease underwent ESWT (group 1). Fifteen patients matched with the baseline characteristic of the patients in group 1, who received no treatment, were used as the control (group 2). The patients' erectile function (International Index of Erectile Function [IIEF-5] score), pain severity (visual analog scale), plaque size and degree of penile angulation were assessed before and after the treatment in group 1 and during the follow-up in group 2.

RESULTS

The mean follow-up time was 32 months (range: 6-64 months) in group 1 and 35 months (range: 9-48 months) in group 2. All the patients were available for the follow-up. Considering erectile function and plaque size, no significant changes (P > 0.05) were observed in group 1 before or after the ESWT. A total of 39 patients (74%) reported a significant effect in pain relief in group 1 after ESWT. However, regarding improvement in pain, IIEF-5 score and plaque size, no significant differences were observed between the two groups. In 21 patients (40%) of group 1, the deviation angle was decreased more than 10 degrees with a mean reduction in all patients of 11 degrees (range: 6-20 degrees). No serious complications were noted considering ESWT procedure.

CONCLUSION

ESWT is a minimally invasive and safe alternative procedure for the treatment of Peyronie's disease. However, the effect of ESWT on penile pain, sexual function and plaque size remains questionable.

Authors+Show Affiliations

Department of Urology, Nordwest Krankenhaus, Steinbacher Hohl 2-26, Frankfurt am Main D-60488, Germany. poulakis@em.uni-frankfurt.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

16625288

Citation

Poulakis, Vassilis, et al. "Extracorporeal Shockwave Therapy for Peyronie's Disease: an Alternative Treatment?" Asian Journal of Andrology, vol. 8, no. 3, 2006, pp. 361-6.
Poulakis V, Skriapas K, de Vries R, et al. Extracorporeal shockwave therapy for Peyronie's disease: an alternative treatment? Asian J Androl. 2006;8(3):361-6.
Poulakis, V., Skriapas, K., de Vries, R., Dillenburg, W., Ferakis, N., Witzsch, U., Melekos, M., & Becht, E. (2006). Extracorporeal shockwave therapy for Peyronie's disease: an alternative treatment? Asian Journal of Andrology, 8(3), 361-6.
Poulakis V, et al. Extracorporeal Shockwave Therapy for Peyronie's Disease: an Alternative Treatment. Asian J Androl. 2006;8(3):361-6. PubMed PMID: 16625288.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Extracorporeal shockwave therapy for Peyronie's disease: an alternative treatment? AU - Poulakis,Vassilis, AU - Skriapas,Konstantinos, AU - de Vries,Rachelle, AU - Dillenburg,Wolfgang, AU - Ferakis,Nikolaos, AU - Witzsch,Ulrich, AU - Melekos,Michael, AU - Becht,Edward, PY - 2006/4/21/pubmed PY - 2006/8/23/medline PY - 2006/4/21/entrez SP - 361 EP - 6 JF - Asian journal of andrology JO - Asian J Androl VL - 8 IS - 3 N2 - AIM: To determine retrospectively the safety and efficacy of extracorporeal shock wave therapy (ESWT) in patients with Peyronie's disease. METHODS: Fifty-three patients with stable Peyronie's disease underwent ESWT (group 1). Fifteen patients matched with the baseline characteristic of the patients in group 1, who received no treatment, were used as the control (group 2). The patients' erectile function (International Index of Erectile Function [IIEF-5] score), pain severity (visual analog scale), plaque size and degree of penile angulation were assessed before and after the treatment in group 1 and during the follow-up in group 2. RESULTS: The mean follow-up time was 32 months (range: 6-64 months) in group 1 and 35 months (range: 9-48 months) in group 2. All the patients were available for the follow-up. Considering erectile function and plaque size, no significant changes (P > 0.05) were observed in group 1 before or after the ESWT. A total of 39 patients (74%) reported a significant effect in pain relief in group 1 after ESWT. However, regarding improvement in pain, IIEF-5 score and plaque size, no significant differences were observed between the two groups. In 21 patients (40%) of group 1, the deviation angle was decreased more than 10 degrees with a mean reduction in all patients of 11 degrees (range: 6-20 degrees). No serious complications were noted considering ESWT procedure. CONCLUSION: ESWT is a minimally invasive and safe alternative procedure for the treatment of Peyronie's disease. However, the effect of ESWT on penile pain, sexual function and plaque size remains questionable. SN - 1008-682X UR - https://wwww.unboundmedicine.com/medline/citation/16625288/Extracorporeal_shockwave_therapy_for_Peyronie's_disease:_an_alternative_treatment L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=16625288.ui DB - PRIME DP - Unbound Medicine ER -