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Effects of dietary carbohydrate on delayed onset muscle soreness and reactive oxygen species after contraction induced muscle damage.
Br J Sports Med. 2005 Dec; 39(12):948-53.BJ

Abstract

BACKGROUND

Delayed onset muscle soreness (DOMS) occurs after unaccustomed exercise and has been suggested to be attributable to reactive oxygen species (ROS). Previous studies have shown increased ROS after lengthening contractions, attributable to invading phagocytes. Plasma glucose is a vital fuel for phagocytes, therefore carbohydrate (CHO) status before exercise may influence ROS production and DOMS.

OBJECTIVE

To examine the effect of pre-exercise CHO status on DOMS, ROS production, and muscle function after contraction induced muscle damage.

METHOD

Twelve subjects performed two downhill runs, one after a high CHO diet and one after a low CHO diet. Blood samples were drawn for analysis of malondialdehyde, total glutathione, creatine kinase, non-esterified fatty acids, lactate, glucose, and leucocytes. DOMS and muscle function were assessed daily.

RESULTS

The high CHO diet resulted in higher respiratory exchange ratio and lactate concentrations than the low CHO diet before exercise. The low CHO diet resulted in higher non-esterified fatty acid concentrations before exercise. DOMS developed after exercise and remained for up to 96 hours, after both diets. A biphasic response in creatine kinase occurred after both diets at 24 and 96 hours after exercise. Malondialdehyde had increased 72 hours after exercise after both diets, and muscle function was attenuated up to this time.

CONCLUSIONS

Downhill running resulted in increased ROS production and ratings of DOMS and secondary increases in muscle damage. CHO status before exercise had no effect.

Authors+Show Affiliations

Liverpool John Moores University, Liverpool, UK. gclose@liv.ac.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

16306505

Citation

Close, G L., et al. "Effects of Dietary Carbohydrate On Delayed Onset Muscle Soreness and Reactive Oxygen Species After Contraction Induced Muscle Damage." British Journal of Sports Medicine, vol. 39, no. 12, 2005, pp. 948-53.
Close GL, Ashton T, Cable T, et al. Effects of dietary carbohydrate on delayed onset muscle soreness and reactive oxygen species after contraction induced muscle damage. Br J Sports Med. 2005;39(12):948-53.
Close, G. L., Ashton, T., Cable, T., Doran, D., Noyes, C., McArdle, F., & MacLaren, D. P. (2005). Effects of dietary carbohydrate on delayed onset muscle soreness and reactive oxygen species after contraction induced muscle damage. British Journal of Sports Medicine, 39(12), 948-53.
Close GL, et al. Effects of Dietary Carbohydrate On Delayed Onset Muscle Soreness and Reactive Oxygen Species After Contraction Induced Muscle Damage. Br J Sports Med. 2005;39(12):948-53. PubMed PMID: 16306505.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of dietary carbohydrate on delayed onset muscle soreness and reactive oxygen species after contraction induced muscle damage. AU - Close,G L, AU - Ashton,T, AU - Cable,T, AU - Doran,D, AU - Noyes,C, AU - McArdle,F, AU - MacLaren,D P M, PY - 2005/11/25/pubmed PY - 2006/1/18/medline PY - 2005/11/25/entrez SP - 948 EP - 53 JF - British journal of sports medicine JO - Br J Sports Med VL - 39 IS - 12 N2 - BACKGROUND: Delayed onset muscle soreness (DOMS) occurs after unaccustomed exercise and has been suggested to be attributable to reactive oxygen species (ROS). Previous studies have shown increased ROS after lengthening contractions, attributable to invading phagocytes. Plasma glucose is a vital fuel for phagocytes, therefore carbohydrate (CHO) status before exercise may influence ROS production and DOMS. OBJECTIVE: To examine the effect of pre-exercise CHO status on DOMS, ROS production, and muscle function after contraction induced muscle damage. METHOD: Twelve subjects performed two downhill runs, one after a high CHO diet and one after a low CHO diet. Blood samples were drawn for analysis of malondialdehyde, total glutathione, creatine kinase, non-esterified fatty acids, lactate, glucose, and leucocytes. DOMS and muscle function were assessed daily. RESULTS: The high CHO diet resulted in higher respiratory exchange ratio and lactate concentrations than the low CHO diet before exercise. The low CHO diet resulted in higher non-esterified fatty acid concentrations before exercise. DOMS developed after exercise and remained for up to 96 hours, after both diets. A biphasic response in creatine kinase occurred after both diets at 24 and 96 hours after exercise. Malondialdehyde had increased 72 hours after exercise after both diets, and muscle function was attenuated up to this time. CONCLUSIONS: Downhill running resulted in increased ROS production and ratings of DOMS and secondary increases in muscle damage. CHO status before exercise had no effect. SN - 1473-0480 UR - https://wwww.unboundmedicine.com/medline/citation/16306505/Effects_of_dietary_carbohydrate_on_delayed_onset_muscle_soreness_and_reactive_oxygen_species_after_contraction_induced_muscle_damage_ L2 - https://bjsm.bmj.com/lookup/pmidlookup?view=long&pmid=16306505 DB - PRIME DP - Unbound Medicine ER -