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[Clinical efficacy of a novel hemorheological drug ascovertin in patients with vascular encephalopathy].

Abstract

Patients with stages I and II of vascular encephalopathy developing on the background of atherosclerosis were treated with ascovertin during 21 days. Ascovertin is a complex of flavonoid dihydroquercetin and ascorbic acid. The study group included 21 patients aged 45-65 years and a comparison group consisted of 10 age-matched patients un treated with ascovertin. The ascovertin treatment relieved headache, reduced vertigo and fatigability, improved cognitive functions. The reliable diminishing of whole blood viscosity due to improvement of cellular rheology indices (decrease of aggregation and increase of erythrocyte deformability as well as decrease of indices of lipid peroxidation in erythrocyte membrane and blood plasma) was observed in the stydy group but not in the comparison one.

Authors

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Pub Type(s)

Comparative Study
English Abstract
Journal Article

Language

rus

PubMed ID

15847324

Citation

Plotnikov, M B., et al. "[Clinical Efficacy of a Novel Hemorheological Drug Ascovertin in Patients With Vascular Encephalopathy]." Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova, vol. 104, no. 12, 2004, pp. 33-7.
Plotnikov MB, Plotnikov DM, Alifirova VM, et al. [Clinical efficacy of a novel hemorheological drug ascovertin in patients with vascular encephalopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2004;104(12):33-7.
Plotnikov, M. B., Plotnikov, D. M., Alifirova, V. M., Aliev, O. I., Maslov, M. I. u., Vasil'ev, A. S., & Tiukavkina, N. A. (2004). [Clinical efficacy of a novel hemorheological drug ascovertin in patients with vascular encephalopathy]. Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova, 104(12), 33-7.
Plotnikov MB, et al. [Clinical Efficacy of a Novel Hemorheological Drug Ascovertin in Patients With Vascular Encephalopathy]. Zh Nevrol Psikhiatr Im S S Korsakova. 2004;104(12):33-7. PubMed PMID: 15847324.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical efficacy of a novel hemorheological drug ascovertin in patients with vascular encephalopathy]. AU - Plotnikov,M B, AU - Plotnikov,D M, AU - Alifirova,V M, AU - Aliev,O I, AU - Maslov,M Iu, AU - Vasil'ev,A S, AU - Tiukavkina,N A, PY - 2005/4/26/pubmed PY - 2005/5/14/medline PY - 2005/4/26/entrez SP - 33 EP - 7 JF - Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova JO - Zh Nevrol Psikhiatr Im S S Korsakova VL - 104 IS - 12 N2 - Patients with stages I and II of vascular encephalopathy developing on the background of atherosclerosis were treated with ascovertin during 21 days. Ascovertin is a complex of flavonoid dihydroquercetin and ascorbic acid. The study group included 21 patients aged 45-65 years and a comparison group consisted of 10 age-matched patients un treated with ascovertin. The ascovertin treatment relieved headache, reduced vertigo and fatigability, improved cognitive functions. The reliable diminishing of whole blood viscosity due to improvement of cellular rheology indices (decrease of aggregation and increase of erythrocyte deformability as well as decrease of indices of lipid peroxidation in erythrocyte membrane and blood plasma) was observed in the stydy group but not in the comparison one. SN - 1997-7298 UR - https://wwww.unboundmedicine.com/medline/citation/15847324/[Clinical_efficacy_of_a_novel_hemorheological_drug_ascovertin_in_patients_with_vascular_encephalopathy]_ L2 - https://medlineplus.gov/vitaminc.html DB - PRIME DP - Unbound Medicine ER -