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Questionable efficacy of extracorporeal shock wave therapy for Peyronie's disease: results of a prospective approach.
J Urol. 2004 Jan; 171(1):296-9.JU

Abstract

PURPOSE

Extracorporeal shock wave therapy (ESWT) for Peyronie's disease is still a topic of debate. We evaluated the effects of ESWT in a large series of patients with Peyronie's disease via a prospective approach.

MATERIALS AND METHODS

In a prospective study 114 patients with Peyronie's disease were treated with ESWT. Baseline and followup examinations included ultrasound, and measurement of plaque size and curvature. Symptomatology was evaluated based on a standardized interview. A Minilith SL1 (Storz Medical AG, Kreuzlingen, Switzerland) lithotriptor was used with 4,000 shock waves at a maximum energy level of 0.17 mJ/mm2 applied per session.

RESULTS

A total of 96 patients were available for followup. Considering the total study group no significant changes in penile curvature, plaque size or sexual function were observed despite significant improvements in patients with a curvature of 31 to 60 degrees. Penile pain ceased in 76% of the affected patients.

CONCLUSIONS

According to our data ESWT does not appear to be significantly effective for decreasing penile curvature and plaque size or improving sexual function in the total population of patients with Peyronie's disease despite improvements in individuals. Penile pain seems to resolve earlier than during the natural course. Regarding the results of this study and previous reports with exact documentation of the clinical findings it can be concluded that ESWT cannot be recommended as a standard procedure for Peyronie's disease. To evaluate the exact efficacy of ESWT a controlled, single-blind, multicenter study with exact documentation of symptoms is urgently required.

Authors+Show Affiliations

Department of Urology, Justus Leibig University, Ulm, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

14665898

Citation

Hauck, Ekkehard W., et al. "Questionable Efficacy of Extracorporeal Shock Wave Therapy for Peyronie's Disease: Results of a Prospective Approach." The Journal of Urology, vol. 171, no. 1, 2004, pp. 296-9.
Hauck EW, Hauptmann A, Bschleipfer T, et al. Questionable efficacy of extracorporeal shock wave therapy for Peyronie's disease: results of a prospective approach. J Urol. 2004;171(1):296-9.
Hauck, E. W., Hauptmann, A., Bschleipfer, T., Schmelz, H. U., Altinkilic, B. M., & Weidner, W. (2004). Questionable efficacy of extracorporeal shock wave therapy for Peyronie's disease: results of a prospective approach. The Journal of Urology, 171(1), 296-9.
Hauck EW, et al. Questionable Efficacy of Extracorporeal Shock Wave Therapy for Peyronie's Disease: Results of a Prospective Approach. J Urol. 2004;171(1):296-9. PubMed PMID: 14665898.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Questionable efficacy of extracorporeal shock wave therapy for Peyronie's disease: results of a prospective approach. AU - Hauck,Ekkehard W, AU - Hauptmann,Arne, AU - Bschleipfer,Thomas, AU - Schmelz,Hans U, AU - Altinkilic,Bora M, AU - Weidner,Wolfgang, PY - 2003/12/11/pubmed PY - 2004/1/30/medline PY - 2003/12/11/entrez SP - 296 EP - 9 JF - The Journal of urology JO - J Urol VL - 171 IS - 1 N2 - PURPOSE: Extracorporeal shock wave therapy (ESWT) for Peyronie's disease is still a topic of debate. We evaluated the effects of ESWT in a large series of patients with Peyronie's disease via a prospective approach. MATERIALS AND METHODS: In a prospective study 114 patients with Peyronie's disease were treated with ESWT. Baseline and followup examinations included ultrasound, and measurement of plaque size and curvature. Symptomatology was evaluated based on a standardized interview. A Minilith SL1 (Storz Medical AG, Kreuzlingen, Switzerland) lithotriptor was used with 4,000 shock waves at a maximum energy level of 0.17 mJ/mm2 applied per session. RESULTS: A total of 96 patients were available for followup. Considering the total study group no significant changes in penile curvature, plaque size or sexual function were observed despite significant improvements in patients with a curvature of 31 to 60 degrees. Penile pain ceased in 76% of the affected patients. CONCLUSIONS: According to our data ESWT does not appear to be significantly effective for decreasing penile curvature and plaque size or improving sexual function in the total population of patients with Peyronie's disease despite improvements in individuals. Penile pain seems to resolve earlier than during the natural course. Regarding the results of this study and previous reports with exact documentation of the clinical findings it can be concluded that ESWT cannot be recommended as a standard procedure for Peyronie's disease. To evaluate the exact efficacy of ESWT a controlled, single-blind, multicenter study with exact documentation of symptoms is urgently required. SN - 0022-5347 UR - https://wwww.unboundmedicine.com/medline/citation/14665898/Questionable_efficacy_of_extracorporeal_shock_wave_therapy_for_Peyronie's_disease:_results_of_a_prospective_approach_ L2 - https://www.jurology.com/doi/10.1097/01.ju.0000099891.68488.4e?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -