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Treatment of Peyronie's disease by extracorporeal shockwave therapy: evaluation of our preliminary results.
J Endourol. 1999 Oct; 13(8):549-52.JE

Abstract

BACKGROUND

Peyronie's disease is an idiopathic disorder of the penis that produces erectile dysfunction. It affects mainly the tunica albuginea. We describe our preliminary results with extracorporal shockwave therapy (ESWT) as a new noninvasive modality for the treatment of Peyronie's disease.

PATIENTS AND METHODS

In this study, 24 patients aged 36 to 67 years were treated with ESWT on the Lithostar overhead-module (Siemens). All our patients had unsuccessful medical treatment before ESWT. The average plaque was 7x15 mm. The number of shockwaves ranged from 15,000 to 25,000 (18-21 kV) delivered in four to ten sessions. Most patients needed local anesthesia before therapy.

RESULTS

Four patients (17%) showed marked improvement and complete remission of the penile deviation. Six patients (25%) showed partial remission with painless erections after treatment. Four patients had painless erections after treatment but still had some penile deviation. In 10 patients (41%), ESWT failed, necessitating subsequent penile surgery.

CONCLUSIONS

Our preliminary results with a response rate of 59% with ESWT for Peyronie's disease, including a 17% complete remission rate, is encouraging. However, further multicenter studies will have to prove if ESWT is a real therapeutic option for this disease.

Authors+Show Affiliations

Urology Department, Klinikum Heilbronn, University at Heidelberg, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article

Language

eng

PubMed ID

10597123

Citation

Abdel-Salam, Y, et al. "Treatment of Peyronie's Disease By Extracorporeal Shockwave Therapy: Evaluation of Our Preliminary Results." Journal of Endourology, vol. 13, no. 8, 1999, pp. 549-52.
Abdel-Salam Y, Budair Z, Renner C, et al. Treatment of Peyronie's disease by extracorporeal shockwave therapy: evaluation of our preliminary results. J Endourol. 1999;13(8):549-52.
Abdel-Salam, Y., Budair, Z., Renner, C., Frede, T., Rassweiler, J., El-Annany, F., El-Magraby, H., & El-Akkad, M. (1999). Treatment of Peyronie's disease by extracorporeal shockwave therapy: evaluation of our preliminary results. Journal of Endourology, 13(8), 549-52.
Abdel-Salam Y, et al. Treatment of Peyronie's Disease By Extracorporeal Shockwave Therapy: Evaluation of Our Preliminary Results. J Endourol. 1999;13(8):549-52. PubMed PMID: 10597123.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Treatment of Peyronie's disease by extracorporeal shockwave therapy: evaluation of our preliminary results. AU - Abdel-Salam,Y, AU - Budair,Z, AU - Renner,C, AU - Frede,T, AU - Rassweiler,J, AU - El-Annany,F, AU - El-Magraby,H, AU - El-Akkad,M, PY - 1999/12/22/pubmed PY - 1999/12/22/medline PY - 1999/12/22/entrez SP - 549 EP - 52 JF - Journal of endourology JO - J Endourol VL - 13 IS - 8 N2 - BACKGROUND: Peyronie's disease is an idiopathic disorder of the penis that produces erectile dysfunction. It affects mainly the tunica albuginea. We describe our preliminary results with extracorporal shockwave therapy (ESWT) as a new noninvasive modality for the treatment of Peyronie's disease. PATIENTS AND METHODS: In this study, 24 patients aged 36 to 67 years were treated with ESWT on the Lithostar overhead-module (Siemens). All our patients had unsuccessful medical treatment before ESWT. The average plaque was 7x15 mm. The number of shockwaves ranged from 15,000 to 25,000 (18-21 kV) delivered in four to ten sessions. Most patients needed local anesthesia before therapy. RESULTS: Four patients (17%) showed marked improvement and complete remission of the penile deviation. Six patients (25%) showed partial remission with painless erections after treatment. Four patients had painless erections after treatment but still had some penile deviation. In 10 patients (41%), ESWT failed, necessitating subsequent penile surgery. CONCLUSIONS: Our preliminary results with a response rate of 59% with ESWT for Peyronie's disease, including a 17% complete remission rate, is encouraging. However, further multicenter studies will have to prove if ESWT is a real therapeutic option for this disease. SN - 0892-7790 UR - https://wwww.unboundmedicine.com/medline/citation/10597123/Treatment_of_Peyronie's_disease_by_extracorporeal_shockwave_therapy:_evaluation_of_our_preliminary_results_ L2 - https://www.liebertpub.com/doi/10.1089/end.1999.13.549?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -